Volume 5 Issue 3
May  1984
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CHEN Que, ZHOU Qi-lin, JIA Xian-li ZHENG De-cun. Inhibition of DNA Repair Ability of Human Esophageal Cancer Cell and CHO-K1 Cell by Hyperthermia. Zoological Research, 1984, 5(3): 227-232.
Citation: CHEN Que, ZHOU Qi-lin, JIA Xian-li ZHENG De-cun. Inhibition of DNA Repair Ability of Human Esophageal Cancer Cell and CHO-K1 Cell by Hyperthermia. Zoological Research, 1984, 5(3): 227-232.

Inhibition of DNA Repair Ability of Human Esophageal Cancer Cell and CHO-K1 Cell by Hyperthermia

  • Received Date: 1900-01-01
  • Rev Recd Date: 1900-01-01
  • Publish Date: 1984-08-22
  • Suspension samples of human esophageal cancer cell strain Eca-109 Were treated,before or after 8,000 rad 60 Co γ-irradiation,with 44° or 42℃ for 30 minutes and then incubated in growth medium at 37℃ for 1.5 hours.The 44° treatment inhibited the DNA rejoining repair completely.The 42℃ treatment inhibited it by about 60%,and the uninhibited portion could be repaired during the 42°treatment after irradiation.The suspension samples of CHO-K1 cell were treated,before UV-irradiation (about 50 J/M2),with 44°or 42℃ for 30 minutes and then incubated in growth medium containing 3H-TdR (1μCi/ml) at 37℃ for 3 hours.The 44°treatment inhibited the DNA excision repair completely.The 42°treatment inhibited it incompletely.
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