Global view on virus infection in non-human primates and implications for public health and wildlife conservation

Zhi-Jin Liu; Xue-Kun Qian; Min-Heng Hong; Jia-Li Zhang; Da-Yong Li; Tian-Han Wang; Zuo-Min Yang; Li-Ye Zhang; Zi-Ming Wang; Hua-Jian Nie; Ke-Yue Fan; Xiong-Fei Zhang; Meng-Meng Chen; Wei-Lai Sha; Christian Roos; Ming Li

doi:10.24272/j.issn.2095-8137.2021.080

Volume 42 Issue 5

Sep. 2021

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Article Navigation > Zoological Research > 2021 > 42(5): 626-632

Zhi-Jin Liu, Xue-Kun Qian, Min-Heng Hong, Jia-Li Zhang, Da-Yong Li, Tian-Han Wang, Zuo-Min Yang, Li-Ye Zhang, Zi-Ming Wang, Hua-Jian Nie, Ke-Yue Fan, Xiong-Fei Zhang, Meng-Meng Chen, Wei-Lai Sha, Christian Roos, Ming Li. Global view on virus infection in non-human primates and implications for public health and wildlife conservation. Zoological Research, 2021, 42(5): 626-632. doi: 10.24272/j.issn.2095-8137.2021.080

Citation:

Zhi-Jin Liu, Xue-Kun Qian, Min-Heng Hong, Jia-Li Zhang, Da-Yong Li, Tian-Han Wang, Zuo-Min Yang, Li-Ye Zhang, Zi-Ming Wang, Hua-Jian Nie, Ke-Yue Fan, Xiong-Fei Zhang, Meng-Meng Chen, Wei-Lai Sha, Christian Roos, Ming Li. Global view on virus infection in non-human primates and implications for public health and wildlife conservation. Zoological Research, 2021, 42(5): 626-632. doi: 10.24272/j.issn.2095-8137.2021.080

Citation:

Zhi-Jin Liu, Xue-Kun Qian, Min-Heng Hong, Jia-Li Zhang, Da-Yong Li, Tian-Han Wang, Zuo-Min Yang, Li-Ye Zhang, Zi-Ming Wang, Hua-Jian Nie, Ke-Yue Fan, Xiong-Fei Zhang, Meng-Meng Chen, Wei-Lai Sha, Christian Roos, Ming Li. Global view on virus infection in non-human primates and implications for public health and wildlife conservation. Zoological Research, 2021, 42(5): 626-632. doi: 10.24272/j.issn.2095-8137.2021.080

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Global view on virus infection in non-human primates and implications for public health and wildlife conservation

doi: 10.24272/j.issn.2095-8137.2021.080

Zhi-Jin Liu^{1, 2, 3, #
,
,},
Xue-Kun Qian^{2, 3, #},
Min-Heng Hong^{1, #},
Jia-Li Zhang^{3, 4},
Da-Yong Li⁵,
Tian-Han Wang¹,
Zuo-Min Yang⁶,
Li-Ye Zhang⁷,
Zi-Ming Wang^{3, 4},
Hua-Jian Nie¹,
Ke-Yue Fan¹,
Xiong-Fei Zhang¹,
Meng-Meng Chen^{4, 8},
Wei-Lai Sha⁶,
Christian Roos^{7, 9},
Ming Li^{3, 10
,
,}

1.
College of Life Sciences, Capital Normal University, Beijing 100048, China
2.
College of Life Sciences, Hebei University, Baoding, Hebei 071002, China
3.
CAS Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Beijing 100101, China
4.
University of Chinese Academy of Sciences, Beijing 100049, China
5.
College of Life Sciences, China West Normal University, Nanchong, Sichuan 637009, China
6.
College of Life Sciences, Qufu Normal University, Qufu, Shandong 273100, China
7.
Primate Genetics Laboratory, German Primate Center, Leibniz Institute for Primate Research, Goettingen 37077, Germany
8.
State Key Laboratory of Mycology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China
9.
Gene Bank of Primates, German Primate Center, Leibniz Institute for Primate Research, Goettingen 37077, Germany
10.
Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, Yunnan 650223, China

#Authors contributed equally to this work

Funds: This study was supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (XDA23080201, XDA19050202), National Natural Science Foundation of China (31821001) and National Key R&D Program of China (2016YFC0503200)

More Information

Corresponding author: E-mail: 6888@cnu.edu.cn; lim@ioz.ac.cn
Received Date: 2021-05-31
Accepted Date: 2021-08-18

Published Online: 2021-08-19

Publish Date: 2021-09-18

Abstract

Abstract

Viruses can be transmitted from animals to humans (and vice versa) and across animal species. As such, host-virus interactions and transmission have attracted considerable attention. Non-human primates (NHPs), our closest evolutionary relatives, are susceptible to human viruses and certain pathogens are known to circulate between humans and NHPs. Here, we generated global statistics on virus infections in NHPs (VI-NHPs) based on a literature search and public data mining. In total, 140 NHP species from 12 families are reported to be infected by 186 DNA and RNA virus species, 68.8% of which are also found in humans, indicating high potential for crossing species boundaries. The top 10 NHP species with high centrality in the NHP-virus network include two great apes (Pan troglodytes, Pongo pygmaeus) and eight Old World monkeys (Macaca mulatta, M. fascicularis, M. leonina, Papio cynocephalus, Cercopithecus ascanius, C. erythrotis, Chlorocebus aethiops, and Allochrocebus lhoesti). Given the wide distribution of Old World monkeys and their frequent contact with humans, there is a high risk of virus circulation between humans and such species. Thus, we suggest recurring epidemiological surveillance of NHPs, specifically Old World monkeys that are in frequent contact with humans, and other effective measures to prevent potential circulation and transmission of viruses. Avoidance of false positives and sampling bias should also be a focus in future work.
- Inter-species transmission,
- Emerging infectious diseases,
- Zoonosis,
- Pandemic,
- NHP,
- Virus,
- One Health

#Authors contributed equally to this work

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References(38)

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