酶标法观察尖吻蝮出血毒素I对毛细血管的作用
The effect of hemorrhagin I (Agkistrodon acutus) in capillaries peroxidase conjugated methods
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摘要: 从尖吻蝮蛇毒中分离得到的出血毒素I(AaHI)具有破坏血管系统并造成广泛出血的作用.本文报道用辣根过氧化酶标记的AaHI可以特异地结合在毛细血管内皮细胞外膜上,由此推测内皮细胞膜上存在HaHI的受体或作用位点.Abstract: Hemorrhagin I (AsHI) isolated from A. acutus venom causes repture of vascular system and extensive hemorrhage. The specific attachment of HRP-AaHI to the endothelial cell by the method of horseradish peroxidase conjugation is reported in this paper. The results suggest that receptor of binding site of hemorrhagin I might be present on the outer-membrane of endothelial cell.