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Morphine addiction in non-human primates using rhesus monkeys

WU Xu-Jun ZONG Wei SUN Yong-Mei HU Xin-Tian MA Yuan-Ye WANG Jian-Hong

WU Xu-Jun, ZONG Wei, SUN Yong-Mei, HU Xin-Tian, MA Yuan-Ye, WANG Jian-Hong. Morphine addiction in non-human primates using rhesus monkeys. Zoological Research, 2012, 33(1): 89-91. doi: 10.3724/SP.J.1141.2012.01089
Citation: WU Xu-Jun, ZONG Wei, SUN Yong-Mei, HU Xin-Tian, MA Yuan-Ye, WANG Jian-Hong. Morphine addiction in non-human primates using rhesus monkeys. Zoological Research, 2012, 33(1): 89-91. doi: 10.3724/SP.J.1141.2012.01089

恒河猕猴吗啡成瘾模型的初步建立

doi: 10.3724/SP.J.1141.2012.01089
基金项目: 973 项目(2011CB707800)和中国科学院知识创新工程重要方向项目(KSCX2-EW-J-23)
详细信息
  • 中图分类号: Q959.832; Q959.848; R-331

Morphine addiction in non-human primates using rhesus monkeys

  • 摘要: 吗啡成瘾的非人灵长类动物恒河猕猴(Macaca mulatta)模型的实验结果表明, 猕猴可建立吗啡条件化位置偏好(conditioned place preference, CPP), 且其与吗啡线索相关的记忆可持续(36.3±1.3)月。该研究可以为药物成瘾研究提供有效的非人灵长类动物行为模型。
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出版历程
  • 收稿日期:  2011-12-19
  • 修回日期:  2012-01-05
  • 刊出日期:  2012-02-22

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