LIANG Song-ping, QIN Yu-bing, ZHANG Dong-yi, PAN Xin, CHEN Xiang-ding, XIE Jing-yun. 1993. Biological Characterization of Spider (Selenocosmia huwena) Crude Venom. Zoological Research, 14(1): 60-65.
Citation: LIANG Song-ping, QIN Yu-bing, ZHANG Dong-yi, PAN Xin, CHEN Xiang-ding, XIE Jing-yun. 1993. Biological Characterization of Spider (Selenocosmia huwena) Crude Venom. Zoological Research, 14(1): 60-65.

Biological Characterization of Spider (Selenocosmia huwena) Crude Venom

  • A method of collect venom from the spider (Selenocosmia huwena) was reported.The biological activities of the crude venom were analyzed.The LD50 of the venom in mice and cockroach were 1.16 mg/kg and 300 μg/g respectively.It has enzyme activities of hyaluronidase,alkaline phosphatase,protease.and DNAse,but no choline esterase and phospholipase A were found in it.In the isolated toad sciatic nerve-sartorius preparation the venom at a concentration of 3 mg/mL was found to block the neuromuscular transmission irreversibly.In mice,the crude venom in dosage of 5 mg/kg caused respiratory failure in about 20 seconds.
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