BAO Cheng-xin, Ronald A.Hutton. 1991. Comparative Studies of The Inhibition of Four Vipera russelli Venoms on Platelet Aggregation. Zoological Research, 12(1): 61-66.
Citation: BAO Cheng-xin, Ronald A.Hutton. 1991. Comparative Studies of The Inhibition of Four Vipera russelli Venoms on Platelet Aggregation. Zoological Research, 12(1): 61-66.

Comparative Studies of The Inhibition of Four Vipera russelli Venoms on Platelet Aggregation

  • The inhibition of RVV from different source on platelet aggregation induced by ADP,Collagen or Ristocetin were studied.RVV-B,RVV-S and RVV-Styp could inhibited aggregation induced by above reagents.RVV-T could inhibited aggregation induced by ADP and Collagen,but not by Ristocetin.Platelets preincubated with RVV were resuspended in PPP after washed.It was observed that platelets preincubated with RVV-Styp could entirely restored to respond to Ristocetin,but only partially with RVV-B and RVV-S.These results shown that two distinct platelet inhibitory activities in RVV exist,the mechanism of the inhibition could involved platelet,plasma and other factors.
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