昆明水源水和自来水水质致突变性及化学背景值:I.Ames试验和水源水及自来水微量有机、无机污染物化学背景值

Mutagenicity and Background Content Chemicals of Water Quality of Source Water and Tap Water in Kunming Ⅰ.Ames test and chemical background value of inorganic and organic micro-pollutants in source water of and tap water

摘要: 本文报道，用XAD-2离子树脂吸附富集法制备自来水和滇池及松华坝水库源水提取物，以Ames鼠伤寒沙门氏菌回复突变系统诱发致突变性，Ames试验结果如下：来自滇池源水经氯化的自来水提取物，用TA98菌株加S9或不加S9混合物，突变率>2，结果为阳性。滇池源水提取物致突变性为可疑。使用化学分析法结合生物分析法评价昆明自来水和滇池及松华坝水库水中的化学微量污染物，估价在水中的微量污染物对人体健康的潜在致癌效应是有意义的。

Abstract: Concentrated extracts from tap water and their source water from Dianchi Lake and Songhuaba Reservoir were prepared through adsoption onto XAD-2 resin and tested for their mutagenicity with Ames Salmonella His+ reversion system.The results are as follows:The extract of chlorinated tap water from Dianchi Lake source water showed mutagenic activity towards TA98 with or without S9 mix.The results are positive.The mutagenicity of extract of source water from Dianchi Lake is ambiguous.If taking upper confidetial limit for evaluation,it is positive.The other groups were negative in comparison with the control group.The bioassays were paralleled with chemical analysis,which were used in survey of chemical micro-pollutants in tap water and their sources.These results are concerned with the effects of genetoxicity of micro-pollutants in water on public health.