Abstract: By use of starch gel electrophoresis, the patterns of expression of nine isozymic systems (LDH,MDH,ADH,IDH, GTDH, IDDH,G2PDH,SOD,EST) were investigated in six differentiated adult tissues(brain, eye,muscle, heart, liver and kidney) and the early parently exhibit a tissue specific expression. During the early develomental stages, LDH,IDH, IDDH, SOD and G3PDH isozymes are present but exhibit no evident develomental change. The above results provide basic information for the population genetic structure and population evolution of Megalobrama skolkovii.