三碱基体的模型和能力学研究
The Investigation of Triplet-base Model and Energetics
-
摘要: 三碱基体是形成三链DNA结构的基元,对其进行模型能力学研究具有一定的意义。本文在理论上给出了22种三碱基体,其中有16种已见文献报道。通过构型能量优化、进而作总能量和氢键能的计算,比较了这些三碱基体的相对稳定性和氢键能。Abstract: It is significant to study the model and energetics of the triplet-base,an element of forming three-stranded DNA structure.This paper,at theory,presented 22 kinds of triplet-bases,16 of which have been reported in references.The relative stability and hydrogen bond energy of these triplet-bases have been compared by optimizing their configurational energy and computing the total and hydrogene bond energy.