中缝背核对猫小脑浦肯野细胞电活动的影响

Influence of Dorsal Raphe Nucleus on Electrical Activity of the Cerebellar Purkinje Cell in The Cat

摘要: 在麻醉并麻痹的猫上观察到：刺激中缝背核（DR）可引起小脑皮层浦肯野细胞（PC）兴奋或抑制（主要是抑制）；由被动性腕关节屈伸运动刺激引起的外周本体性传入可以增强或减弱PC对DR刺激的反应。这些结果表明中缝-小脑5-HT能纤维的传入活动可以调制PC的放电活动，并与外周传入有相互作用。

Abstract: In thiopentone-anaesthetized and curarized cats we found that dorsal raphe (DR) stimulation could elicit long latency inhibitory,and in fewer cases,excitatory responses in cerebellar Purkinje cells (PC),and the peripheral inputs elicited by passive forepaw flexion-extension movements may enhance or reduce the response of PCs to DR stimulation.The results suggest that the raphe-cerebellar serotonergic fiber may modulate PCs activity and interact with the peripheral input.