• 中文核心期刊要目总览
  • 中国科技核心期刊
  • 中国科学引文数据库(CSCD)
  • 中国科技论文与引文数据库(CSTPCD)
  • 中国学术期刊文摘数据库(CSAD)
  • 中国学术期刊(网络版)(CNKI)
  • 中文科技期刊数据库
  • 万方数据知识服务平台
  • 中国超星期刊域出版平台
  • 国家科技学术期刊开放平台
  • 荷兰文摘与引文数据库(SCOPUS)
  • 日本科学技术振兴机构数据库(JST)
马旭通, 李福林, 蒋宏君, 李文辉, 张云, 杜廷义. 2011: 野生和人工繁育树鼩部分生理指标检测与比较. 动物学研究, 32(1): 4-10. DOI: 10.3724/SP.J.1141.2011.01004
引用本文: 马旭通, 李福林, 蒋宏君, 李文辉, 张云, 杜廷义. 2011: 野生和人工繁育树鼩部分生理指标检测与比较. 动物学研究, 32(1): 4-10. DOI: 10.3724/SP.J.1141.2011.01004
MA Xu-Tong, LI Fu-Lin, JIANG Hong-Jun, LI Wen-Hui, ZHANG Yun, DU Ting-Yi. 2011: Detection and comparison of physiological indexes in the wild and laboratory tree shrew. Zoological Research, 32(1): 4-10. DOI: 10.3724/SP.J.1141.2011.01004
Citation: MA Xu-Tong, LI Fu-Lin, JIANG Hong-Jun, LI Wen-Hui, ZHANG Yun, DU Ting-Yi. 2011: Detection and comparison of physiological indexes in the wild and laboratory tree shrew. Zoological Research, 32(1): 4-10. DOI: 10.3724/SP.J.1141.2011.01004

野生和人工繁育树鼩部分生理指标检测与比较

Detection and comparison of physiological indexes in the wild and laboratory tree shrew

  • 摘要: 比较野生和人工繁育树鼩的部分生理指标, 为人类疾病的动物模型创制提供基本参数。血液采自昆明地区54只野生树鼩 (被捕获后人工饲养1—2月)和54只子一代人工繁育树鼩。该研究首次报道在两组动物中, 肌酸激酶、肌钙蛋白I、总胆汁酸、果糖胺、低密度脂蛋白胆固醇等在性别间差异无显著性;这些指标在人工繁育树鼩中的中位数 (四分位数间距) 依次为:1449 (956) U/L、5.94 (7.23) μg/L、15.6 (19.7) μmol/L、393.5 (80.8) μmol/L和0.36 (0.32) mmol/L; 在野生树鼩中依次为:986 (564) U/L、4.01 (4.10) μg/L、20.0 (20.6) μmol/L、379.0 (104.0) μmol/L和0.46 (0.23) mmol/L。人工繁育树鼩生理指标表现出个体间离散程度降低趋势, 但个别反映肝脏功能及心肌情况的指标表现出平均值上升, 个体离散程度扩大的现象。这些生理指标为人类疾病的树鼩模型创制打下了基础。

     

    Abstract: To provide fundamental basis for the tree shrew models of human diseases, we examined and compared the physiological and biochemical indexes between wild and laboratory tree shrews. Blood samples were taken from 54 wild tree shrews that were housed in laboratory for 1 − 2 months, and from 54 first-generation of the laboratory tree shrews; each group had nearly equal male and female composition. Some of the first reported physiological and biochemical indexes were showed no significant differences between genders, and these indexes in laboratory tree shrews were as follows medium (inter-quartile range) : CK 1449 (956) U/L, CTNI 5.94 (7.23) μg/L, TBA15.6 (19.7) μmol/L, FRUC 393.5 (80.8) μmol/L and LDL-C0.36 (0.32); and in the wild tree shrews, 986 (564) U/L, 4.01 (4.10) μg/L, 20.0 (20.6) μmol/L, 379.0 (104.0) μmol/L and 0.46 (0.23) mmol/L, respectively. In the laboratory tree shrews, the variations of physiological and biochemical indexes were smaller, but the mean values of some indicators related to liver and heart functions became higher. These data would be valuable for the development of tree shrew models of human diseases.

     

/

返回文章
返回