ZHENG Yuan-Lin, HAN Zheng-Kang, CHEN Jie, AI Xiao-Jie, LIU Gen-Tao. 2001. Effects of Clenbuterol on IGF-Ⅰ,GH and Insulin Level of Hepatic Blood in Sheep. Zoological Research, 22(3): 246-249.
Citation: ZHENG Yuan-Lin, HAN Zheng-Kang, CHEN Jie, AI Xiao-Jie, LIU Gen-Tao. 2001. Effects of Clenbuterol on IGF-Ⅰ,GH and Insulin Level of Hepatic Blood in Sheep. Zoological Research, 22(3): 246-249.

Effects of Clenbuterol on IGF-Ⅰ,GH and Insulin Level of Hepatic Blood in Sheep

  • Four sheep installed chronic catheters in the portal vein,hepatic vein and mesenteric vein were used to study the effects of clenbuterol on metabolic hormones.The results are:1)The GH level of portal vein is markedly increased during clenbuterol treatment period (0.8 mg/kg BW,twice daily for five days);2)The GH level of hepatic vein with clenbuterol-treated is similar to that of control;3)The IGF-Ⅰ concentration of hepatic vein is markedly elevated and IGF-Ⅰ of portal vein is maintained a higher level in clenbuterol treatment period.4)The insulin concentration of hepatic blood is decreased with clenbuterol-treated.These showed that the changes of those hormone levels in clenbuterol treatment played an important role in regulation of growth and metabolism in sheep.
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