LI Hong-fang, WANG Long-de, QIN Xiao-min. 1998: Effect of Prostaglandin E1 On Rat's Antral Myoelectric Activity. Zoological Research, 19(6): 434-438.
Citation: LI Hong-fang, WANG Long-de, QIN Xiao-min. 1998: Effect of Prostaglandin E1 On Rat's Antral Myoelectric Activity. Zoological Research, 19(6): 434-438.

Effect of Prostaglandin E1 On Rat's Antral Myoelectric Activity

  • The effect of abdomnoinjection prostaglandin E1(PGE1) on antral myoelectric activity was investigated in 30 Wistar rats chronically implanted with Ag/AgCl bipolar electrode on the serosal surface of antrum.It was found that PGE1 could 1) decrease the amplitude of slow wave;2) cause biphasic changes of fast wave,usually with enhancement before giving way to inhibition;3) cause diarrhea.The inhibitory action of PGE1 on slow wave and fast wave might be not mediated via adrenergic α and β receptor,and the excitatory action of PGE1 on fast wave was probably mediated via cholinergic M receptor.
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