Volume 1 Issue 3
May  1980
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CAI Jing-xia, SUN Xin, YANG Chang-jiu, CHEN Xi-lan, LI Chao-da, ZHAO Qi-kun, TIAN Yun-fen et al.. Column Chromatography Fractionation of Ophiophagus Hannan Venom and Study of Neurotoxic Peaks. Zoological Research, 1980, 1(3): 319-325.
Citation: CAI Jing-xia, SUN Xin, YANG Chang-jiu, CHEN Xi-lan, LI Chao-da, ZHAO Qi-kun, TIAN Yun-fen et al.. Column Chromatography Fractionation of Ophiophagus Hannan Venom and Study of Neurotoxic Peaks. Zoological Research, 1980, 1(3): 319-325.

Column Chromatography Fractionation of Ophiophagus Hannan Venom and Study of Neurotoxic Peaks

  • Received Date: 1900-01-01
  • Rev Recd Date: 1900-01-01
  • Publish Date: 1980-08-22
  • We fractionated Chinese Guangxi Ophiophagus hannah venom by CM-Sephadex C-25 column chromatography.Linear gradient elution was carried out with NaCl.Seventeen protein peaks were obtained.Their toxicity and physiological activities were estimated.Of the seven toxic peaks,six had the effect of blockading the transmission of neuromuscle juncture.The other one was much less toxic.It didnt show such effect with the same dose.
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    沈阳化工大学材料科学与工程学院 沈阳 110142

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Column Chromatography Fractionation of Ophiophagus Hannan Venom and Study of Neurotoxic Peaks

Abstract: We fractionated Chinese Guangxi Ophiophagus hannah venom by CM-Sephadex C-25 column chromatography.Linear gradient elution was carried out with NaCl.Seventeen protein peaks were obtained.Their toxicity and physiological activities were estimated.Of the seven toxic peaks,six had the effect of blockading the transmission of neuromuscle juncture.The other one was much less toxic.It didnt show such effect with the same dose.

CAI Jing-xia, SUN Xin, YANG Chang-jiu, CHEN Xi-lan, LI Chao-da, ZHAO Qi-kun, TIAN Yun-fen et al.. Column Chromatography Fractionation of Ophiophagus Hannan Venom and Study of Neurotoxic Peaks. Zoological Research, 1980, 1(3): 319-325.
Citation: CAI Jing-xia, SUN Xin, YANG Chang-jiu, CHEN Xi-lan, LI Chao-da, ZHAO Qi-kun, TIAN Yun-fen et al.. Column Chromatography Fractionation of Ophiophagus Hannan Venom and Study of Neurotoxic Peaks. Zoological Research, 1980, 1(3): 319-325.

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