Jinling CAO, Jianjie CHEN, Zhongliang JIANG, Yongju LUO, Xi GAN. Molecularcloning and expression analysis of FTZ-F1 in the GIFT tilapia, Oreochromis niloticus. Zoological Research, 2012, 33(E3-4): 40-46. doi: 10.3724/SP.J.1141.2012.E03-04E40
Citation: Jinling CAO, Jianjie CHEN, Zhongliang JIANG, Yongju LUO, Xi GAN. Molecularcloning and expression analysis of FTZ-F1 in the GIFT tilapia, Oreochromis niloticus. Zoological Research, 2012, 33(E3-4): 40-46. doi: 10.3724/SP.J.1141.2012.E03-04E40

Molecularcloning and expression analysis of FTZ-F1 in the GIFT tilapia, Oreochromis niloticus

doi: 10.3724/SP.J.1141.2012.E03-04E40
Funds:  the Natural Science Foundation of Shanxi Province, China (2009021038); the Doctor Initial Foundation of Shanxi Agricultural University (XB2009003); the Science and Technology Innovational Foundation of Shanxi Agricultural University (2009005); the Nonprofit Research Institutes, Special Foundation for Operating Expenses of Basic Research Projects of Guangxi Zhuang Autonomous Region(2060302 GXIF-2008-01); the Scientific Research and Technological Development Projects of Nanning City(200801016B)
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  • Author Bio:

    Jinling CAO

  • Corresponding author: Jinling CAO
  • Received Date: 2012-02-27
  • Rev Recd Date: 2012-06-01
  • Publish Date: 2012-08-10
  • The FTZ-F1 genes encode orphan receptors of the nuclear receptor superfamily and in mammals have been found to play important roles in the proper development of the adrenal-gonadal axis and sex-determination. We isolated the homologue of FTZ-F1 in genetically improved farmed tilapia (gfFTZ-F1). The full-length cDNA was isolated from the ovary, which included an open reading frame encoding a predicted protein of 486 amino acids. Sequence, tissue distribution and phylogenic analysis of the FTZ-F1 showed that the gfFTZ-F1 belonged to SF-1/Ad4BP group and that gfFTZ-F1 transcripts were only expressed in the gonads and kidney but not in other tissues. Likewise our data suggests that the gfFTZ-F1 gene may share similar functions with other fish and mammalian counterparts, though further study is needed to make any definitive conclusions.
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