Volume 33 Issue 4
Jul.  2012
Turn off MathJax
Article Contents
YU Yu, SUO Lun, WU Qiang. Protocadherin x gene cluster is required for myelination and oligodendrocyte development. Zoological Research, 2012, 33(4): 362-366. doi: 10.3724/SP.J.1141.2012.04362
Citation: YU Yu, SUO Lun, WU Qiang. Protocadherin x gene cluster is required for myelination and oligodendrocyte development. Zoological Research, 2012, 33(4): 362-366. doi: 10.3724/SP.J.1141.2012.04362

Protocadherin x gene cluster is required for myelination and oligodendrocyte development

doi: 10.3724/SP.J.1141.2012.04362
More Information
  • Author Bio:

    YU Yu,E-mail: sduyuyu@yahoo.com.cn

  • Corresponding author: WU Qiang
  • Received Date: 2012-04-20
  • Rev Recd Date: 2012-07-06
  • Publish Date: 2012-08-10
  • This work used Immunohistochemistry to examine the expression of myelin basic protein and accumulation of oligodendrocytes in Pchdaknockout and control littermate mice. Data showed that in Pchda knockout mice, Myelin proteins decrease in the central nervous systemand mature oligodendrocytes in the cerebellum also decrease. Furthermore, deletion of the Pcdha cluster does not cause any change to the axons and astrocytes in quantification of relative marker proteins. These findings suggest that the Pcdha cluster may be required for myelination and oligodendrite development of the brain in mice, and that Pcdha cluster may play a key role in the development of the central nervous system.
  • loading
  • Relative Articles

    [1] Ting Song, Jun Zhou. Primary cilia in corneal development and disease. Zoological Research, 2020, 41(5): 495-502.  doi: 10.24272/j.issn.2095-8137.2020.109
    [2] Wei-Ye LI, Yi-Quan WANG. Establishment of full-sib families of Branchiostoma japonicum and the relationship between early development patterns and larvae survival rates. Zoological Research, 2013, 34(5): 446-452.  doi: 10.11813/j.issn.0254-5853.2013.5.0446
    [3] SONG Hai-Yan, LIU Zai-Qun, ZHENG Lei. Expression of IFN-γ, IL-1α, NGF-β and TNF-α during the development of cerebellar cortex of Western Anhui white goose. Zoological Research, 2012, (2): 211-217.  doi: 10.3724/SP.J.1141.2012.02211
    [4] WEI Li, RU Bing-hua, ZHOU Ying-ying, SHAO Wei-wei, ZHANG Li-biao, HONG Tiyu, ZHOU S. Postnatal Development of Morphological Features and Vocalization of Rhinolophus pusillus. Zoological Research, 2009, 30(1): 91-98.  doi: 10.3724/SP.J.1141.2009.01091
    [5] ZHAO Zhi-jun, WANG Rui-rui, CAO Jing, PEI Lan-ying. Effect of Random Food Deprivation and Refeeding on Energy Budget and Development in Mice. Zoological Research, 2009, 30(5): 534-538.  doi: 10.3724/SP.J.1141.2009.05534
    [6] HU Bing, YANG Xiao-zhen, WU Xu-gan, TENG Wei-ming, CHENG Yong-xu. Development of Gonad in Different Body Weights of Onchidium struma. Zoological Research, 2008, 29(2): 145-151.  doi: 10.3724/SP.J.1141.2008.02145
    [7] WEN Ru-shu, FANG Zhan-qiang, CHEN Wei-ting. Effects of 17β-estradiol on Vitellogenin Inducement and Gonad Development in Male Tanichthys albonubes. Zoological Research, 2008, 29(1): 43-48.
    [8] YAO Gui-gui, WU Xu-gan, YANG Xiao-zhen, CHENG Yong-xu, *, WANG Chun-lin. The Second Ovarian Development of Swimming Crab, Portunus trituberculatus. Zoological Research, 2007, 28(4): 423-429.
    [9] HUA Tian-miao, WANG Chao-lin, CHEN Bi-hui. Stages of Embryonic Development for Alligator sinensis. Zoological Research, 2004, 25(3): 263-271.
    [10] MENG Fan-Li, ZHAO Yun-Long, CHEN Li-Qiao, GU Zhi-Min, XU Gu-Xing, LIU Qi-Wen. Embryonic Development of Redclaw Crayfish Cherax quadricarinatus:Ⅱ.Development of Digestive System. Zoological Research, 2001, 22(5): 383-387.
    [11] WU Xin-Fu, LI Tian-Fei, WEI Jia-Ning, WANG Yi, DENG Jian-Hua, GAO Jia-He, ZHAO Li-Heng. Temperature Effects on Development and Fecundity of Aphidius gifuensis Ashmead. Zoological Research, 2000, 21(3): 192-198.
    [12] ZHOU Xiao-ming, SUN Xin-de. The Influence on The Characteristics of Frequency Tuning of Bats'inferior Collicular Neurons by Early Sound Exposure. Zoological Research, 1997, 18(1): 59-64.
    [13] FENG Qing, WANG Ying-xiang, LI Chong-yun. Postnatal Growth and Development in The Intermediate Slow Loris (Nycticebus intermedius) in Captivity. Zoological Research, 1996, 17(4): 443-450.
    [14] ZHONG Ming-chao, HUANG Zhe. Induced Development of Pigment Macrophage Aggregate (Pma) in Adult and Juvenile of the Freshwater Catfish Silurus asotus L.. Zoological Research, 1996, 17(2): 153-167.
    [15] Rao dingqi, Yang datong. The study of early development and evolution of Torrentophryne aspinia. Zoological Research, 1994, 15(zk): 142-157.
    [16] HAN Ya-li, TAN Zhu-jun. A Study on The isoenzyme During Embryonic Development of Rana chensinensis. Zoological Research, 1993, 14(1): 66-72.
    [17] ZHANG Mei-fen, WU Mei-xi, DING Han-bo. Study on The Development of Gynogenesis Haploid of Misgurnus anguillicaudatus. Zoological Research, 1993, 14(4): 361-366.
    [18] LIU Guo-an, LIU Yun-qing, HU Di-guang, XIONG Wen-hua. A Preliminary Observation on the Development of the Embryo of Tortoise,Chinemys reevesii. Zoological Research, 1984, 5(1): 51-56.
    [19] RONG Shou-bai, LIU Xing-chao. Observations and Studies on the Embryonic Development of Gryllotalpa unispina Saussure. Zoological Research, 1984, 5(3): 211-218.
    [20] WANG Cheng-lun, WANG Hui-xie, WANG Ye-an, LU Hong. Studies no the Relationship of Temperature and Development of Trichocramma Dendorlimi Matsumura. Zoological Research, 1981, 2(4): 317-326.
  • 加载中


    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (1846) PDF downloads(2563) Cited by()
    Proportional views


    DownLoad:  Full-Size Img  PowerPoint