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Progress on nonhuman primate models of diabetes mellitus

LIANG Bin WU Xiao-Yun

LIANG Bin, WU Xiao-Yun. Progress on nonhuman primate models of diabetes mellitus. Zoological Research, 2011, 32(1): 91-96. doi: 10.3724/SP.J.1141.2011.01091
Citation: LIANG Bin, WU Xiao-Yun. Progress on nonhuman primate models of diabetes mellitus. Zoological Research, 2011, 32(1): 91-96. doi: 10.3724/SP.J.1141.2011.01091

非人灵长类糖尿病动物模型研究进展

doi: 10.3724/SP.J.1141.2011.01091
基金项目: 中国科学院知识创新工程重要方向项目(KSCX2-EW-R-12)资助;中国科学院基础前沿研究专项项目(KSCX2-EW-J-23);中国科学院和云南省动物模型与人类疾病机理重点实验室资助项目
详细信息
    作者简介:

    梁 斌,博士, 研究员,Email:liangb@mail.kiz.ac.cn

    通讯作者:

    梁 斌,博士, 研究员

  • 中图分类号: R-332; R587.1; Q959.848

Progress on nonhuman primate models of diabetes mellitus

More Information
    Author Bio:

    LIANG Bin,Email:liangb@mail.kiz.ac.cn

    Corresponding author: LIANG Bin
  • 摘要: 糖尿病是继心血管疾病和肿瘤之后的另一种严重危害人类健康的重要慢性疾病, 据世界卫生组织(WHO)报道, 2009年全世界约有2.2亿糖尿病患者。对糖尿病发病机理的研究、预防和诊断、治疗药物的筛选和评价都需要合适的动物模型。在已报道的糖尿病动物模型中, 非人灵长类动物糖尿病病程、病症与人类的糖尿病最为相似。该文从糖尿病动物模型的来源归纳了目前报道的主要的非人灵长类糖尿病模型, 重点介绍了猕猴、食蟹猴和树鼩糖尿病模型及其特征, 并对该领域的发展提出了一些思考。
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出版历程
  • 收稿日期:  2010-11-23
  • 修回日期:  2010-12-31
  • 刊出日期:  2011-02-22

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