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Detection and comparison of physiological indexes in the wild and laboratory tree shrew

MA Xu-Tong LI Fu-Lin JIANG Hong-Jun LI Wen-Hui ZHANG Yun DU Ting-Yi

MA Xu-Tong, LI Fu-Lin, JIANG Hong-Jun, LI Wen-Hui, ZHANG Yun, DU Ting-Yi. Detection and comparison of physiological indexes in the wild and laboratory tree shrew. Zoological Research, 2011, 32(1): 4-10. doi: 10.3724/SP.J.1141.2011.01004
Citation: MA Xu-Tong, LI Fu-Lin, JIANG Hong-Jun, LI Wen-Hui, ZHANG Yun, DU Ting-Yi. Detection and comparison of physiological indexes in the wild and laboratory tree shrew. Zoological Research, 2011, 32(1): 4-10. doi: 10.3724/SP.J.1141.2011.01004

野生和人工繁育树鼩部分生理指标检测与比较

doi: 10.3724/SP.J.1141.2011.01004
基金项目: 中国科学院知识创新工程重要方向项目(KSCX2-EW-R-11);中国科学院基础前沿研究专项项目(KSCX2-EW-J-23);中国科学院和云南省动物模型与人类疾病机理重点实验室资助项目
详细信息
    作者简介:

    马旭通 (1984—), 男, 硕士研究生, 研究方向为生物化学与分子生物学, E-mail:mxt07@126.com

    通讯作者:

    张 云, 杜廷义

  • 中图分类号: Q95-33; Q959.832

Detection and comparison of physiological indexes in the wild and laboratory tree shrew

More Information
    Author Bio:

    MA Xu-Tong(1984-),E-mail:mxt07@126.com

    Corresponding author: ZHANG Yun,DU Ting-Yi
  • 摘要: 比较野生和人工繁育树鼩的部分生理指标, 为人类疾病的动物模型创制提供基本参数。血液采自昆明地区54只野生树鼩 (被捕获后人工饲养1—2月)和54只子一代人工繁育树鼩。该研究首次报道在两组动物中, 肌酸激酶、肌钙蛋白I、总胆汁酸、果糖胺、低密度脂蛋白胆固醇等在性别间差异无显著性;这些指标在人工繁育树鼩中的中位数 (四分位数间距) 依次为:1449 (956) U/L、5.94 (7.23) μg/L、15.6 (19.7) μmol/L、393.5 (80.8) μmol/L和0.36 (0.32) mmol/L; 在野生树鼩中依次为:986 (564) U/L、4.01 (4.10) μg/L、20.0 (20.6) μmol/L、379.0 (104.0) μmol/L和0.46 (0.23) mmol/L。人工繁育树鼩生理指标表现出个体间离散程度降低趋势, 但个别反映肝脏功能及心肌情况的指标表现出平均值上升, 个体离散程度扩大的现象。这些生理指标为人类疾病的树鼩模型创制打下了基础。
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出版历程
  • 收稿日期:  2010-12-01
  • 修回日期:  2010-12-29
  • 刊出日期:  2011-02-22

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