Volume 18 Issue 1
Jan.  1997
Turn off MathJax
Article Contents
CAO Yu-jing, JIANG Guang-tai, ZENG Guo-qing. Inhibition of Mouse Implantation by Proteinase Inhibitors. Zoological Research, 1997, 18(1): 93-98.
Citation: CAO Yu-jing, JIANG Guang-tai, ZENG Guo-qing. Inhibition of Mouse Implantation by Proteinase Inhibitors. Zoological Research, 1997, 18(1): 93-98.

Inhibition of Mouse Implantation by Proteinase Inhibitors

  • Received Date: 1900-01-01
  • Rev Recd Date: 1900-01-01
  • Publish Date: 1997-02-22
  • In this study,we examined effects of several proteinase inhibitors on implantation of mouse.We found that proteinase inhibitors soybean trypsin inhibitor (STI),ε-aminocaproic acid (EACA) and nitrophenol-p-guanidino benzoate (NPGB) could significantly inhibit mouse implantation when injected into uterine during pre-implantaion.We also found that NPGB could significantly inhibit attachment and outgrowth of blastocysts on the uterine epithelia cell monolayer when added into co-culture system,and STI and EACA only inhibited the outgrowth of blastocysts on the uterine epithelia cell monolayer.These results suggested that proteolytic activities were involved in implantation,some proteinases such as trypsin and plasminogen activator had important functions during trophoblast invasion.
  • loading
  • Relative Articles

    [1] Fang DING, Li CHEN, Yong LIU, Feng-Rui WU, Biao DING, Wen-Yong LI, Rong WANG. Effects of alcohol on H3K9 acetylation in mouse pre-implantation embryos. Zoological Research, 2015, 36(1): 54-58.  doi: 10.13918/j.issn.2095-8137.2015.1.54
    [2] Wen-Qing ZHANG, Yi-Fu GONG, Li ZHANG, Jun LI, Xiao-Dan LIU. Cloning and expression analysis of the NFκB inhibitor IκBα of ayu (Plecoglossus altivelis). Zoological Research, 2013, 34(4): 399-405.  doi: 10.11813/j.issn.0254-5853.2013.4.0399
    [3] WANG Xi-Hong, HE Xie-Chao, HAN Shu-Biao, JI Wei-Zhi, ZHENG Ping. Role of PTEN in mouse pre-implantation development. Zoological Research, 2011, 32(6): 647-650.  doi: 10.3724/SP.J.1141.2011.06647
    [4] XIA Hou-JUN, ZHANG Gao-Hong, ZHENG Yong-Tang. Roles of Dendritic Cell in Disease Progression of AIDS Primate Models. Zoological Research, 2010, 31(1): 57-65.  doi: 10.3724/SP.J.1141.2010.01057
    [5] DU Chen-guang, YANG Yan-yan, LI Hai-jun, BAO Qing-jiang. Expression of the Ghrelin in Sheep Ooctyes and Pre-implantation Embryos Produced in vivo. Zoological Research, 2008, 29(2): 134-138.  doi: 10.3724/SP.J.1141.2008.02134
    [6] WANG Li-ju, GAO Guo-fu, BAI Shi-ping, LIU Zhi-gang, LIANG Jian-guo et al.. A Thrombin Inhibitor from Ixodid Tick,Ixodide sinesis. Zoological Research, 2005, 26(3): 328-331.
    [7] LI Jing-Yan. The Significance of Studying the Origin of the Cell Nucleus and the Way for Studying. Zoological Research, 2001, 22(1): 77-82.
    [8] ZHENG De-shu. Apoptosis and Programmed Cell Death. Zoological Research, 2000, 21(1): 17-22.
    [9] LI Jing-yan. Diplomonads and The Exploration on The Origin of Cell Nucleus. Zoological Research, 1996, 17(3): 275-286.
    [10] ZHANG Ping-cheng, CHENG Ying-jun, FANG Ye, WANG Zhong-huai, BAI Chun-li. Atomic Force Microscope (AFM) and Applications in Cell Biology. Zoological Research, 1993, 14(zk): 58-66.
    [11] ZHAO Xiao-fan. Purification of A Cysteine Proteinase From Eggs of Silkmoth (Bombyx mori) and Preparation of The Antiserum. Zoological Research, 1993, 14(1): 93-95.
    [12] ZHANG Dong-lei, WANG Qi-zheng, CHENG Jian-zhi. Enzymatic Properties and Biological Activities of A Proteolytic Enzyme (Proteinase A) From The Venom of Agkistrodon Halys Pallas. Zoological Research, 1992, 13(4): 381-385.
    [13] LI Jing-yan. The Proposal of Evolutionary Cell Blology and Its Role. Zoological Research, 1989, 10(4): 319-326.
    [14] ZHUO Zhao-wen, CHENG Ming-zhe et al., PANG Fu-xiong, WU Shi-hai et al.. Trypsin Inhibitor in Hydrophis cyanocinctus Venom. Zoological Research, 1988, 9(4): 426-436.
    [15] ZHU Su-tian, LU Qun, XIANG Wei. Establishment of Avian Feather Pulp Culture Method and Study on the Cell Division. Zoological Research, 1987, 8(1): 21-26.
    [16] ZHANG Xi-ran, WANG Jian-hua, CHEN Yu-ze, SHI Li-ming. Cytogenetic Characteristics of two Cell Lines of the Mosquito (Aedes albopictus). Zoological Research, 1984, 5(zk): 39-44.
    [17] CHEN Que, ZHOU Qi-lin, JIA Xian-li ZHENG De-cun. Inhibition of DNA Repair Ability of Human Esophageal Cancer Cell and CHO-K1 Cell by Hyperthermia. Zoological Research, 1984, 5(3): 227-232.
    [18] YE Yin-ying, MAO Yi-ping, LU Xiao-xuan, WANG Shi-juan. The Observation of Biological Characteristics of Hybrid Cell in Mice. Zoological Research, 1984, 5(4): 319-324.
    [19] LI Ling-yan. Cell Theory. Zoological Research, 1982, 3(zk): 373-374.
    [20] XUE Kai-xian. Experimental studies on Cell Growth and cell Division in Amoeba discoides. Zoological Research, 1980, 1(1): 65-74.
  • 加载中


    通讯作者: 陈斌, bchen63@163.com
    • 1. 

      沈阳化工大学材料科学与工程学院 沈阳 110142

    1. 本站搜索
    2. 百度学术搜索
    3. 万方数据库搜索
    4. CNKI搜索

    Article Metrics

    Article views (2047) PDF downloads(1403) Cited by()
    Proportional views


    DownLoad:  Full-Size Img  PowerPoint