Zoological Research ›› 2019, Vol. 40 ›› Issue (2): 70-76.doi: 10.24272/j.issn.2095-8137.2018.069

• Commentary •     Next Articles

Current understanding on the roles of gut microbiota in fish disease and immunity

Jin-Bo Xiong1, Li Nie1,2, Jiong Chen1,2,*   

  1. 1 Laboratory of Biochemistry and Molecular Biology, School of Marine Sciences, Ningbo University, Ningbo 315211, China
    2 Key Laboratory of Applied Marine Biotechnology of Ministry of Education, Ningbo University, Ningbo 315211, China
  • Online:2019-03-18 Published:2019-01-11
  • Contact: Jiong Chen,E-mail:jchen1975@163.com E-mail:jchen1975@163.com
  • Supported by:
     

Abstract:

Intensive aquaculture has increased the severity and frequency of fish diseases. Given the functional importance of gut microbiota in various facets of host physiology, modulation of this microbiota is a feasible strategy to mitigate emerging diseases in aquaculture. To achieve this, a fundamental understanding of the interplay among fish health, microbiota, and invading pathogens is required. This mini-review focuses on current knowledge regarding the associations between fish diseases, dysbiosis of gut microbiota, and immune responses. Furthermore, updated research on fish disease from an ecological perspective is discussed, including colonization resistance imposed by commensals and strategies used by pathogens to overcome resistance. We also propose several directions for future research, such as exploration of the causal links between fish diseases and specific taxa, and identification of universal gut microbial biomarkers for rapid disease diagnosis.

Key words: Fish disease, Gut microbiota, Immune response, Colonization resistance, Universal microbial biomarkers

CLC Number: 

  •  
[1] Yan-Fang Cui, Feng-Jie Wang, Lei Yu, Hua-Hu Ye, Gui-Bo Yang. Metagenomic comparison of the rectal microbiota between rhesus macaques (Macaca mulatta) and cynomolgus macaques (Macaca fascicularis) [J]. Zoological Research, 2019, 40(2): 89-93.
[2] YAO Cui-luan ,WANG Zhi-yong ,*,XIANG Jian-hai. Crustacean Haemocytes and Their Function in Immune Responses [J]. Zoological Research, 2006, 27(5): 549-557.
Viewed
Full text


Abstract

Cited

  Shared   
  Discussed   
[1] ZHOU Wei*,PAN Xiao-fu,OU Xiao-hong,ZHANG Qing. Comparison of Food Components Between Rana pleuraden and Rana chaochiaoensis from Kunming and Evaluation of Their Benefit and Harm[J]. Zoological Research, 2007, 28(1): 28 -34 .
[2] XIONG Yu-liang,WANG Wan-yu,YANG Chang-jin,TIEN Yun-fen. Inhibitory Effects of The Elapidae Venoms in The Mice's Sarcoma 180 Ehrilich Ascititers Carcenoma[J]. Zoological Research, 1989, 10(1): 31 -35 .
[3] ZHU Shi-mo,HUANG Fi-sheng. Effect of Geological Vicissitude on Orignation of Termite from Yunnan,China[J]. Zoological Research, 1989, 10(1): 1 -8 .
[4] WU Xue-feng,ZHAO Jin-liang,QIAN Ye-zhou,WU Chao. Histological Study of the Digestive System Organogenesis for the Mandarin Fish,Siniperca chuatsi[J]. Zoological Research, 2007, 28(5): 511 -518 .
[5] . New Proof for Astrocytes Having L-type Calcium Channels[J]. Zoological Research, 2007, 28(5): 485 -490 .
[6] . Phylogentic Relationships of Butterflies in the Subfamily Elymninae (Lepidoptera: Satyridae) Based on Mitochondrial ND1 and COI Gene Sequences[J]. Zoological Research, 2007, 28(5): 477 -484 .
[7] LI Xiao-juan,ZHOU Cai-quan,JIN Li-guang. Avian Diversity and Bird Strike Avoidance in Gaoping Airport of Nanchong in Autumn and Winter[J]. Zoological Research, 2007, 28(6): 615 -625 .
[8] LIU Zhao,ZHOU Wei,ZHANG Qing,LI Jin-xiang,LI Ning,ZHANG Reng-gong. Selection and Plant Community Characteristics of Foraging Sites for Hume’s Pheasant (Syramticus humiae) in Nanhua Part of Ailaoshan National Nature Reserve[J]. Zoological Research, 2008, 29(6): 646 -652 .
[9] ZHOU Jiang,CHAN Bosco Pui Lok,WEI Fu-wen. Responses to Inter-group Encounters of the Hainan Gibbon Nomascus hainanus[J]. Zoological Research, 2008, 29(6): 667 -673 .
[10] LIU Shu-bai ,HE Ying-ying ,QIAN Jin-qiao ,,LEE Wen-hui,ZHANG Yun. Research Progression of Non-lens βγ-crystallins[J]. Zoological Research, 2008, 29(6): 679 -688 .