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ZOOLOGICAL RESEARCH    2010, Vol. 31 Issue (5) : 561-564     DOI: 10.3724/SP.J.1141.2010.05561
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Rates and patterns of microsatellite mutations in common carp (Cyprinus carpio L.)
ZHANG Yan 1,2, LU Cui-Yun 2, CAO Ding-Chen 2, XU Peng 1, WANG Shu 1, LI Heng-De 1, ZHAO Zi-Xia 1 , SUN Xiao-Wen 1,2,*
1. The Centre for Applied Aquatic Genomics, Chinese Academy of Fishery Sciences, Beijing 100141, China; 2. Heilongjiang Fisheries Research Institute, Chinese Academy of Fisheries Sciences, Harbin 150040, China
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During genotyping 150 microsatellites in a F1 family of common carp, six mutations were found at five microsatellite loci. The overall mutation rate of common carp microsatellites was 2.53×10-4 per locus per generation. At five loci, mutations increased the length of alleles by at least one repeat unit, suggesting mutations at microsatellite loci in common carp do not follow strict stepwise mutation model. The data on mutation rates and patterns can facilitate population genetics studies, and provide useful parameters for estimating a long-term effective population size of common carp.
Keywords Mutation rate      Mutation pattern      Common carp     
PACS:  Q959.468  
Corresponding Authors: SUN Xiao-Wen   
Issue Date: 22 October 2010
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ZHANG Yan,LU Cui-Yun,CAO Ding-Chen,XU Peng,WANG Shu,LI Heng-De,ZHAO Zi-Xia. Rates and patterns of microsatellite mutations in common carp (Cyprinus carpio L.)[J]. ZOOLOGICAL RESEARCH,2010, 31(5): 561-564.
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