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ZOOLOGICAL RESEARCH    2010, Vol. 31 Issue (1) : 57-65     DOI: 10.3724/SP.J.1141.2010.01057
Articles |
Roles of Dendritic Cell in Disease Progression of AIDS Primate Models
XIA Hou-JUN 1,2 , ZHANG Gao-Hong 1 , ZHENG Yong-Tang 1,*
1. Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China; 2. Graduate School of the Chinese Academy of Sciences, Beijing 100039, China
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Non-human primate models are widely used in research of AIDS mechanism, transmission, vaccine and drugs. Dendritic cells (DC), as antigen presenting cells linking the innate immunity and acquired immunity, play a pivotal role in AIDS progression. Studies on the change of DC subsets number, phenotype and function in AIDS non-human primate models are important for revealing some mechanism of AIDS progression. This article reviews the progress in DC subsets of non-human primate AIDS models, which will provide an avenue for further study in AIDS.
Keywords AIDS      Human immunodeficiency virus      Simian immunodeficiency virus      Dendritic cells      Primate      Animal models     
Corresponding Authors: ZHENG Yong-Tang   
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XIA Hou-JUN,ZHANG Gao-Hong,ZHENG Yong-Tang. Roles of Dendritic Cell in Disease Progression of AIDS Primate Models. ZOOLOGICAL RESEARCH, 2010, 31(1): 57-65.
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